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Flumatinib Chemical Structure

Flumatinib

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP23797CAS No. ：895519-90-1Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 895519-90-1 Cat. No. BCP23797
Name Flumatinib
Synonyms HHGV678; HHGV 678 ; HHGV-678; HH-GV-678;
SMILES
Chemical Name
Formula C29H29F3N8O M. Wt 562.59
Purity 98% Storage Store at 4-8°C
Description Flumatinib, also known as HHGV678 , is a selective inhibitor of BCR-ABL/PDGFR/KIT. Flumatinib is currently in Phase I and II clinical trials in China for the treatment of chronic myelogenous leukemia (CML). Flumatinib effectively overcomes drug resistance of certain KIT mutants. Flumatinib mesylate can reduce the expression of C-MYC, HIF-1 α and VEGF in U266 cell line in a time- and dose-dependent manners.
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