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iCRT3 Chemical Structure

iCRT3

Data Sheet For research use only. Not for human use.
Cat. No. :BCP32691CAS No. :901751-47-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 901751-47-1 Cat. No. BCP32691
Name iCRT3
Synonyms iCRT-3;
SMILES CCC1=CC=C(C=C1)C2=NC(=C(O2)C)CSCC(=O)NCCC3=CC=CC=C3
Chemical Name
Formula C23H26N2O2S M. Wt 394.53
Purity 98% Storage Store at 4-8°C
Description iCRT3 is an inhibitor of the Wnt/wingless signaling pathway. iCRT3 efficiently block Wnt/β-catenin-induced target genes and phenotypes in various mammalian and cancer cell lines. Importantly, these Wnt inhibitors are specifically cytotoxic to human colon tumor biopsy cultures as well as colon cancer cell lines that exhibit deregulated Wnt signaling.
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