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TMCB Chemical Structure

TMCB

Cat. No. :BCP27716CAS No. :905105-89-7Purity:98%
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Synonyms
CAS Number 905105-89-7
Purity 98%
M. Wt 534.83
Formula C11H9Br4N3O2
Storage Store at 4-8°C
TMCB is a dual-kinase inhibitor of both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8) (IC50 = 0.50 μM for both CK2 and ERK8). TMCB exhibits selectivity for CK2 over protein kinases normally susceptible to CK2 inhibitors (Ki = 0.25, 8.65, 11.90 and 15.25 μM for CK2, PIM1, DYRK1a and HIPK2, respectively).

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