SAG New
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 912545-86-9 | Cat. No. | BCP14694 |
| Name | SAG | ||
| Synonyms | SAG free base; SAG (Smo agonist); SAG (cyclopamine antagonist); | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C28H28ClN3OS | M. Wt | 490.06 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | SAG is a potent Smoothened (Smo) receptor agonist (Kd = 59 nM); sag antagonizes cyclopamine action at the Smo receptor. SAG potently activates the Hedgehog signaling pathway in Shh-light 2 cells (EC50 ~ 3 nM). SAG induces pathway activation independently of Ptch proteins. The Smoothened receptor (SMO) mediates signal transduction in the hedgehog pathway, which is implicated in normal development and carcinogenesis. SMO antagonists can suppress the growth of some tumours. | ||
Recommend Products
More >
-
PF-05274857 HCl
Cat. No.：BCP48085
No.：1613439-62-5
Product Details -
-
-
-
-
SAG Hydrochloride
Cat. No.：BCP26130
No.：2095432-58-7
Product Details -
Saridegib
Cat. No.：BCP25392
No.：1037210-93-7
Product Details -
-
-
-
-
LDE225 Diphosphate
Cat. No.：BCP11860
No.：1218778-77-8
Product Details -
LDE225 HCL
Cat. No.：BCP11861
No.：1218778-76-7
Product Details -
Smoothened Agonist HCl
Cat. No.：BCP10857
No.：364590-63-6
Product Details -
-
LY2940680
Cat. No.：BCP02512
No.：1258861-20-9
Product Details -
Purmorphamine
Cat. No.：BCP03687
No.：483367-10-8
Product Details -
PF-04449913
Cat. No.：BCP08388
No.：1095173-27-5
Product Details -
Tags:SAG supplier,SAG purchase,SAG manufacturer,SAG distributor,SAG cost,SAG buy,SAG for sale