Erismodegib New
Data Sheet
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| CAS No. | 956697-53-3 | Cat. No. | BCP02275 |
| Name | Erismodegib | ||
| Synonyms | LDE225;LDE-225;NVP-LDE225;Sonidegib; NVP-LDE-225; NVP LDE225; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C26H26F3N3O3 | M. Wt | 485.5 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Sonidegib, also known as, erismodegib, LDE225, NVP-LDE225, is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity. Erismodegib selectively binds to the Hedgehog (Hh)-ligand cell surface receptor Smo, which may result in the suppression of the Hh signaling pathway and, so, the inhibition of tumor cells in which this pathway is abnormally activated. | ||
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