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ADC Related

Chemical Structure Cat. No. Product Name CAS No.
Auristatin E trifluoroacetate Chemical Structure
 BCP30132 Auristatin E trifluoroacetate AuristatinEt
Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in Antibody-drug conjugates.
Acetylene-linker-Val-Cit-PABC-MMAE Chemical Structure
 BCP20285 Acetylene-linker-Val-Cit-PABC-MMAE 1411977-95-1
Acetylene-linker-Val-Cit-PABC-MMAE consists the ADCs linker (Acetylene-linker-Val-Cit-PABC) and potent tubulin inhibitor (MMAE), Acetylene-linker-Val-Cit-PABC-MMAE is an antibody drug conjugate.
(+/-)Amethopterin Chemical Structure
 BCP29918 (+/-)Amethopterin 60388-53-6
Amethopterin is a chemotherapy agent and immune system suppressant.
DBCO-acid Chemical Structure
 BCP29894 DBCO-acid 1207355-31-4
DBCO acid 2 is a Click Chemistry intermidate used for antibody-drug conjugates..
Aldoxorubici Chemical Structure
 BCP21580 Aldoxorubici 151038-96-9
Aldoxorubicin, also known as INNO-206 and Doxo-EMCH, is a 6-maleimidocaproyl hydrazone derivative of Doxorubicin, is an albumin binding prodrug.
Taltobulin Chemical Structure
 BCP29188 Taltobulin 228266-40-8
Taltobulin (HTI-286; SPA-110) is an analogue of Hemiasterlin; potent tubulin inhibitor; ADCs cytotoxin.
DM1-SMCC Chemical Structure
 BCP09614 DM1-SMCC 1228105-51-8
DM1-SMCC is DM1 with a reactive linker SMCC, which can react with antibody to make antibody drug conjugate.
McMMAE Chemical Structure
 BCP24644 McMMAE 863971-24-8
Mc-MMAE is a protective group (maleimidocaproyl)-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate (ADC).
Camptothecin Chemical Structure
 BCP02857 Camptothecin 7689-03-4
Camptothecin is a potent DNA enzyme topoisomerase I inhibitor with an IC50 and IC70 of 50 nM and 0.225 μM for breast cancer cell line MDA-MB-231.
Ansamitocin P-3 Chemical Structure
 BCP07918 Ansamitocin P-3 66584-72-3
Ansamitocin P-3 is a microtubule inhibitor. Ansamitocin P-3 is a macrocyclic antitumor antibiotic.
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