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AMPK

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AMPK

结构式 货号 产品名称 CAS号
BC1618 结构式
BCP42670 BC1618 2222094-18-8
BC1618 is a novel Fbxo48 inhibitor and prevent pAmpkα degradation with MEC (minimal efficacious concentration) of 0.6 μM.
PF-06679142 结构式
BCP40393 PF-06679142 1467059-66-0
PF-06679142 is a potent AMPK activator.
MT 63-78 结构式
BCP38015 MT 63-78 1179347-65-9
MT 63-78 is a direct activator of AMPK, and an inhibitor of prostate cancer growth by blocking lipogenesis.
IM156 结构式
BCP37661 IM156 1422365-93-2
IM156, a metformin derivative, is a potent activator of AMPK that increases AMPK phosphorylation. IM156 blocks oxidative phosphorylation (OXPHOS) through the inhibition of complex I and increases apoptosis. IM156 ameliorates various types of fibrosis and inhibits tumors.
ASP4132 结构式
BCP35839 ASP4132 1640294-30-9
ASP4132 is an orally active, potent AMPK activator with an EC50 of 18 nM. ASP4132 has anti-cancer activity and makes tumor regression in breast cancer xenograft mouse models.
Urolithin B 结构式
BCP35736 尿石素B 1139-83-9
Urolithin B belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one). Urolithin b is considered to be a practically insoluble (in water) and relatively neutral molecule.
PF-06409577 结构式
BCP32554 PF-06409577 1467057-23-3
PF-06409577 is a potent and selective allosteric activator of AMPK α1β1γ1 isoform with an EC50 of 7 nM.
GSK621 结构式
BCP31970 GSK621 1346607-05-3
GSK621 is a specific and potent AMPK activator.
MOTS-c (human) 结构式
BCP31969 MOTS-c (human) 1627580-64-6
MOTS-c is a Mitochondria-derived peptide (MDP). Promotes biosynthesis of the endogenous AMP analog AICAR and consequently AMP-activated protein kinase (AMPK).
Pterosin B 结构式
BCP09994 蕨素B 34175-96-7
Pterosin B is isolated and purified from the aerial parts of Pteris semipinnata.
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