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Beta catenin

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Beta catenin

结构式 货号 产品名称 CAS号
IWP-4 结构式
BCP43694 IWP-4 686772-17-8
IWP-4 is a novel potent inhibitor of Wnt/β-catenin signaling.
CWP232228 sodium 结构式
BCP43357 CWP232228 sodium 1144044-02-9
CWP232228 is a novel Wnt/β-Catenin inhibitor.
G244-LM 结构式
BCP37837 G244-LM 1563007-08-8
G244-LM is a potent and specific small-molecule tankyrase inhibitors, which reduces Wnt/β-catenin signaling by preventing poly(ADP-ribosyl)ation-dependent AXIN degradation, thereby promoting β-catenin destabilization.
NRX-252262 结构式
BCP36626 NRX-252262 2438637-61-5
NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation, with an EC50 of 3.8 nM.
C-82 结构式
BCP35612 C-82 1422253-37-9
C-82 is a second-generation specific CBP/β-catenin antagonist, which inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300.
KY1220 结构式
BCP34008 KY1220 292168-79-7
KY1220 is a small molecule that simultaneously degrades β-catenin and Ras by inhibition of the Wnt/β-catenin pathway.
Tegatrabetan 结构式
BCP32893 Tegatrabetan 1227637-23-1
Tegatrabetan is a β-Catenin antagonist. Tegatrabetan disrupts the binding of β-catenin with the scaffold protein transducin β-like 1 (TBL1).
WIKI4 结构式
BCP15357 WIKI4 838818-26-1
WIKI4 is a potent inhibitor of Wnt/β-catenin signaling (EC50 ~ 75 nM); inhibits auto-ADP-ribosylation of tankyrase 2 (TNKS2) (IC50 ~15 nM).
IQ-1 结构式
BCP19305 IQ-1 331001-62-8
IQ-1 has many functions such as decreasing Wnt-stimulated phosphorylation, maintaining the pluripotency of murine ESCs, preventing PP2A/Nkd interaction and so on.
Cercosporin 结构式
BCP23993 尾孢菌素 35082-49-6
Cercosporin is a potent, selective competitive PKC inhibitor.
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