首页   >  
Neuro Signaling Pathway
  >  
Beta secretase

所有产品分类

所有产品

信号通路

研究领域

天然产物

抗体

多肽

催化剂

杂质对照品

医药中间体

基础原料

Beta secretase

结构式 货号 产品名称 CAS号
Elenbecestat 结构式
BCP39709 Elenbecestat 1388651-30-6
Elenbecestat is a novel, potent and orally bioavailable BACE1 inhibitor for the treatment of Alzheimer's disease (AD), which demonstrates prolonged reductions in plasma beta-amyloid levels after single dosing.
Atabecestat 结构式
BCP25878 Atabecestat 1200493-78-2
Atabecestat, also known as JNJ-54861911, is a β-site amyloid presursor protein cleaving enzyme 1 (BACE1), an enzyme whose buildup is implicated in Alzheimer’s disease. JNJ-54861911 was found to inhibit BACE1 with approximately 2,600 nM affinity to 1 nM affinity.
Aloeresin D 结构式
BCP32579 芦荟新甙D 105317-67-7
Aloeresin D is isolated and purified from the herbs of Aloe arborescens Mill.
beta-Secretase Inhibitor IV 结构式
BCP31596 beta-Secretase Inhibitor IV 797035-11-1
beta-Secretase Inhibitor IV is a potent, cell-active BACE-1 inhibitor with IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively.
NB-360 HCl 结构式
BCP30332 NB-360 HCl 1262855-97-9
NB-360 is a potent and brain penetrable BACE-1 inhibitor.
AZD3839 结构式
BCP13212 AZD3839 1227163-56-5
AZD3839, with the potential to treat Alzheimer’s disease, was reported as a selective BACE1 inhibitor (IC50=4.8μM) for which concentration-dependent lowering of Ab peptides in cellular systems and three pre-clinical species were demonstrated.
Umibecestat 结构式
BCP30325 Umibecestat 1387560-01-1
Umibecestat, also known as CNP-520, is a beta-secretase inhibitor and is a drug candidate for prevention trials in Alzheimer's disease.
RG7129 结构式
BCP23733 RG7129 1310347-50-2
RG7129 is a potent BACE inhibitor with IC50 of 30 nM for BACE1, equally potent against BACE2 (IC50=40 nM).
Sophoflavescenol 结构式
BCP24815 Sophoflavescenol 216450-65-6
Sophoflavescenol is a prenylated flavonol, which shows great inhibitory activity with IC50 of 0.013 μM against Phosphodiesterase 5 (PDE5), and also inhibits RLAR, HRAR, AGE, BACE1, AChE and BChE with IC50s of 0.30 µM, 0.17 µM, 17.89 µg/mL, 10.98 µM, 8.37 µM and 8.21 µM, respectively.
AZD3839 结构式
BCP23892 AZD3839 1227163-84-9
AZD3839 is a potent and selective BACE1 inhibitor with IC50 of 23.6 uM, about 14-fold selectivity over BACE2, also a β-secretase enzyme inhibitor.
12下一页共 18 条记录 1 / 2 页 
2853530913