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Chemical Structure Cat. No. Product Name CAS No.
NU610 Chemical Structure
BCP31257 NU610 444722-95-6
NU6102 is a potent inhibitor of Cdk1 and Cdk2 with Ki values of 9 and 6 nM and IC50 values of 9.5 and 5.4 nM, respectively.
Cdk2 Inhibitor II Chemical Structure
BCP31226 Cdk2 Inhibitor II 222035-13-4
Cdk2 Inhibitor II is a 3-(benzylidne)indolin-2-one analog that selectively and potently inhibits Cdk2 (IC50 = 60 nM). It is cell permeable, reversible, and ATP-competitive.
Palbociclib 2HCl Chemical Structure
BCP22592 Palbociclib 2HCl 571189-11-2
Palbociclib 2HCl is a cyclin-dependent kinase (CDK) inhibitor with high affinity for CDK4 and CDK6.
MC180295 Chemical Structure
BCP31053 MC180295 2237942-08-2
MC180295 is a potent and selective CDK9-Cyclin T1 inhibitor, with an IC50 of 5 nM, at least 22-fold more selective for CDK9 over other CDKs. MC180295 also inhibits GSK-3α and GSK-3β. MC180295 ((rel)-MC180295) has potent anti-tumor effect.
CDK8-IN-1 Chemical Structure
BCP23512 CDK8-IN-1 1629633-48-2
CDK8-IN-1 is a potent and selective CDK8 inhibitor with an IC50 of 3 nM.
CT7001 hydrochloride Chemical Structure
BCP30944 CT7001 hydrochloride 1805789-54-1
CT7001 hydrochloride is a selective CDK7 inhibitor, with IC50s of 41 nM and 578 nM for CDK7/CycH/MAT1 and CDK2/cycE1, respectively.
ON-013100 Chemical Structure
BCP17288 ON-013100 865783-95-5
ON-013100, an antineoplastic drug, acts a mitotic inhibitor that could inhibit Cyclin D1 expression.
ABC-1183 Chemical Structure
BCP30547 ABC-1183 1042735-18-1
ABC-1183 is a selective dual GSK3α/β and CKD9 inhibitor.
SEL120-34A Chemical Structure
BCP30533 SEL120-34A 1609522-33-9
SEL120-34A is a potent, selective, orally available, ATP-competitive CDK8 inhibitor, with IC50s of 4.4 nM and 10.4 nM for CDK8/CycC and CDK19/CycC, respectively, with antitumor activity.
BSJ-03-123 Chemical Structure
BCP30504 BSJ-03-123 BSJ-03-123
BSJ-03-123 is a potent and novel CDK6-selective small-molecule degrader (PROTAC).
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