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CDK

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CDK

Chemical Structure Cat. No. Product Name CAS No.
Riviciclib Chemical Structure
BCP17903 Riviciclib 920113-02-6
Riviciclib is a flavone and cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity. Riviciclib selectively binds to and inhibits Cdk4/cyclin D1, Cdk1/cyclin B and Cdk9/cyclin T1, serine/threonine kinases that play key roles in the regulation of the cell cycle and cellular proliferation.
(+/-)-Roscovitine Chemical Structure
BCP19053 (+/-)-Roscovitine 186692-44-4
Roscovitine is a potent and selective CDKs inhibitor with IC50s of 0.2 μM, 0.65 μM, and 0.7 μM for CDK5, Cdc2, and CDK2, respectively.
CGP74514A Chemical Structure
BCP20240 CGP74514A 190653-73-7
CGP74514A is a CDK1 inhibitor with potential anticancer activity.
SB1317 Chemical Structure
BCP27919 SB1317 1204918-72-8
SB1317 is a potent inhibitor of CDK2, JAK2, and FLT3 for the treatment of cancer, with IC50 of 13, 73, and 56 nM for CDK2, JAK2 and FLT3, respectively.
TAK-931 Chemical Structure
BCP29654 TAK-931 1330782-76-7
TAK-931 is a selective cycle 7 (CDC7) kinase inhibitor, with an IC50<0.3 nM.
CMPD 7 Chemical Structure
BCP29063 CMPD 7 2220184-50-7
CMPD 7 is a potent and selective CDK12 inhibitor with an IC50 of 491 nM in enzymatic assay.
BI-1347 Chemical Structure
BCP29562 BI-1347 2163056-91-3
BI-1347 is a potent, selective inhibitor of CDK8/cyclinC with IC50 of 1 nM.
CC-671 Chemical Structure
BCP29519 CC-671 1618658-88-0
CC-671 is a potent and selective dual inhibitor of TTK (Mps1) and CLK2.
(+)-BAY-1251152 Chemical Structure
BCP29512 (+)-BAY-1251152 1610358-56-9
(+)-BAY-1251152 is a CDK9 inhibitor extracted from patent WO 2014076091 A1, example 1.
Roniciclib Chemical Structure
BCP28164 Roniciclib 1223498-69-8
Roniciclib, also known as BAY 1000394, is an orally bioavailable cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity.
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