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CDK

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CDK

Chemical Structure Cat. No. Product Name CAS No.
PNU112455A hydrochloride Chemical Structure
BCP32610 PNU112455A hydrochloride 21886-12-4
PNU112455A is an ATP site competetive inhibitor of CDK2 and CDK5.
Longdaysin Chemical Structure
BCP32583 Longdaysin 1353867-91-0
Longdaysin is a novel inhibitor of CK1, ERK2, and CDK7 kinases.
CDK8/19-IN-1 Chemical Structure
BCP23526 CDK8/19-IN-1 1818427-07-4
CDK8/19-IN-1 is a potent, selective and oral bioavailable CDK8/19 dual inhibitor, with IC50s of 0.46 nM, 0.99 nM and 270 nM for CDK8, CDK19 and CDK9, respectively.
SY-1365 Chemical Structure
BCP28906 SY-1365 1816988-80-3
SY-1365 is a novel selective covalent inhibitor of cyclin-dependent kinase 7 (CDK7).
ICEC0942 Chemical Structure
BCP31681 ICEC0942 1805833-75-3
ICEC0942 is a novel selective inhibitor of cdk7.
NU610 Chemical Structure
BCP31257 NU610 444722-95-6
NU6102 is a potent inhibitor of Cdk1 and Cdk2 with Ki values of 9 and 6 nM and IC50 values of 9.5 and 5.4 nM, respectively.
Cdk2 Inhibitor II Chemical Structure
BCP31226 Cdk2 Inhibitor II 222035-13-4
Cdk2 Inhibitor II is a 3-(benzylidne)indolin-2-one analog that selectively and potently inhibits Cdk2 (IC50 = 60 nM). It is cell permeable, reversible, and ATP-competitive.
Palbociclib 2HCl Chemical Structure
BCP22592 Palbociclib 2HCl 571189-11-2
Palbociclib 2HCl is a cyclin-dependent kinase (CDK) inhibitor with high affinity for CDK4 and CDK6.
MC180295 Chemical Structure
BCP31053 MC180295 2237942-08-2
MC180295 is a potent and selective CDK9-Cyclin T1 inhibitor, with an IC50 of 5 nM, at least 22-fold more selective for CDK9 over other CDKs. MC180295 also inhibits GSK-3α and GSK-3β. MC180295 ((rel)-MC180295) has potent anti-tumor effect.
CDK8-IN-1 Chemical Structure
BCP23512 CDK8-IN-1 1629633-48-2
CDK8-IN-1 is a potent and selective CDK8 inhibitor with an IC50 of 3 nM.
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