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CDK

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CDK

Chemical Structure Cat. No. Product Name CAS No.
(±)-BAY-1251152 Chemical Structure
BCP33292 (±)-BAY-1251152 1610358-53-6
(±)-BAY-1251152 is a racemic mixture of BAY-1251152. BAY-1251152 is a potent and highly selective PTEF/CDK9 inhibitor.
Trilaciclib dihydrochloride Chemical Structure
BCP25727 Trilaciclib dihydrochloride 1977495-97-8
Trilaciclib 2HCl is a CDK4/6 inhibitor with IC50s of 1 nM and 4 nM for CDK4 and CDK6, respectively.
JSH-150 Chemical Structure
BCP33243 JSH-150 2247481-21-4
JSH-150 is a potent CDK9 inhibitor.
Alsterpaullone Chemical Structure
BCP33241 Alsterpaullone 237430-03-4
Alsterpaullone, also known as 9-Nitropaullone and NSC 705701, is a derivative of kenpaullone and an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3β (GSK3β).
SR-4835 Chemical Structure
BCP33214 SR-4835 2387704-62-1
SR-4835 is a potent, highly selective and ATP competitive dual inhibitor of CDK12/CDK13 (CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM). SR-4835 acts in synergy with DNA-damaging chemotherapy and PARP inhibitors and provokes triple-negative breast cancer (TNBC) cell death.
 Chemical Structure
NVP-2 Chemical Structure
BCP32927 NVP-2 1263373-43-8
NVP-2 is an inhibitor of the cyclin-dependent kinase, CDK9.
TG693 Chemical Structure
BCP32897 TG693 885272-55-9
TG693 is an orally available, selective, ATP-competitive CLK1 inhibitor.
Lerociclib Chemical Structure
BCP26063 Lerociclib 1628256-23-4
Lerociclib (G1T38) is a potent and selective inhibitor of CDK4/6, with IC50s of 1 nM, 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively.
CDK2 inhibitor 73 Chemical Structure
BCP32769 CDK2 inhibitor 73 2079895-42-2
CDK2 inhibitor 73 is a potent and highly selective CDK2 inhibitor.
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