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Cytochrome P450

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Cytochrome P450

结构式 货号 产品名称 CAS号
CDD3505 结构式
BCP42511 CDD3505 173865-33-3
CDD3505 is used for elevating high density lipoprotein cholesterol (HDL) by inducing hepatic cytochrome P450IIIA (CYP3A) activity.
Dafadine-A 结构式
BCP37926 Dafadine-A 1065506-69-5
Dafadine-A, the first identified chemical inhibitor of DAF-9, could restrain the dauer formation, developmental timing and longevity in the nematodeCaenorhabditis elegans.
Verapamil 结构式
BCP37129 维拉帕米 52-53-9
Verapamil is a calcium channel blocker that is a class IV anti-arrhythmia agent.
PC945 结构式
BCP36481 PC945 1931946-73-4
PC945, a potent, long-acting antifungal triazole, possesses activity against a broad range of both azole-susceptible and azole-resistant strains of Aspergillus fumigatus. PC945 is also a potent, tightly binding inhibitor of A. fumigatus sterol 14α-demethylase activity, CYP51A and CYP51B, with IC50s of 0.23 μM and 0.22 μM, respectively.
Clomethiazole 结构式
BCP36337 氯美噻唑 533-45-9
Chlormethiazole is an potent and orally active GABAA agonist. Chlormethiazole inhibits cytochrome P450 isoforms: CYP2A6 and CYP2E1 in human liver microsomes. Chlormethiazole is an anticonvulsant agent and has the potential for treating convulsive status epilepticus.
DMU2105 结构式
BCP35214 DMU2105 1031063-36-1
DMU2105(CYP1B1 inhibitor 7k) is a potent and specific CYP1B1 inhibitor.
Doxepin-d3 Hydrochloride 结构式
BCP33258 盐酸多虑平D3 347840-07-7
Doxepin D3 Hydrochloride is a deuterium labeled Doxepin Hydrochloride.Doxepin is a tricyclic antidepressant (TCA) used for the treatment of major depression and anxiety.
Phillyrin 结构式
BCP26036 连翘苷 487-41-2
Phillyrin is a natural lignan that has the potential to ameliorate the inflammatory changes and insulin resistance in obese adipose tissue.
(R)-Talarozole 结构式
BCP21218 他拉罗唑 870093-23-5
(R)-Talarozole is a potent and selective inhibitor of cytochrome P450 26-mediated breakdown of endogenous all-trans retinoic acid for the treatment of psoriasis and acne.
20(S)-Ginsenoside C-K 结构式
BCP30926 20(S)-人参皂苷 C-K 39262-14-1
Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. Ginsenoside C-K exhibits an inhibition against the activity of CYP2C9 and CYP2A6 in human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively.
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