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GPR

结构式 货号 产品名称 CAS号
SCO-267 结构式
BCP41795 SCO-267 1656261-09-4
SCO-267 is a novel GPR40 full agonist, improving liver parameters in a mouse model of nonalcoholic fatty liver disease without affecting glucose or body weight.
AS1269574 结构式
BCP43461 AS1269574 330981-72-1
AS-1269574 is a selective, orally available GPR119 agonist with EC50 of 2.5 uM in cell-based cAMP assays.
TAK041 结构式
BCP43188 TAK041 1929519-13-0
TAK-041 is a novel Potent and Selective GPR139 Agonist for the Treatment of Negative Symptoms Associated with Schizophrenia.
PSB-SB-487 结构式
BCP37990 PSB-SB-487 1399049-81-0
PSB-SB-487 is a potent, allosteric GPR55 antagonist
ML-191 结构式
BCP37828 ML-191 931695-79-3
ML-191 is a potent, selective GPR55 antagonist with 160 nM potency for GPR55 and >100-fold selectivity against GPR35, CB1 and CB2.
AMG-009 结构式
BCP37558 AMG-009 1027847-67-1
AMG 009 is an orally active, small molecule CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells) and DP (D prostanoid) dual antagonist, which was in preclinical development in the US for the treatment of asthma and allergic rhinitis.
DC260126 结构式
BCP32685 DC260126 346692-04-4
DC260126 is a FFA1 (GPR40) antagonist.
ALB-127158A 结构式
BCP32660 ALB-127158A 1173154-32-9
ALB-127158A is a potent and selective melanin concentrating hormone 1 (MCH1) receptor antagonist.
GPR120 Agonist 2 结构式
BCP32553 GPR120 Agonist 2 1234844-11-1
GPR120 Agonist 2 is a GPR120 agonist.
ML401 结构式
BCP31489 ML401 1597489-14-9
ML401 is an antagonist of the EBI2 receptor.
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