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HIF

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HIF

Chemical Structure Cat. No. Product Name CAS No.
KHS101 hydrochloride Chemical Structure
BCP30178 KHS101 hydrochloride 1784282-12-7
KHS101 hydrochloride could selectively induce a neuronal differentiation phenotype and interacts with transforming acidic coiled-coil-containing protein 3 (TACC3).
KHS101 Chemical Structure
BCP30177 KHS101 1262770-73-9
KHS-101 is a small molecule that selectively induces a neuronal differentiation phenotype, induces neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs) by interacting with TACC3 (EC50=1 uM).
Desidustat Chemical Structure
BCP29692 Desidustat 1616690-16-4
Desidustat is an inhibitor of HIF hydroxylase extracted from patent WO 2014102818 A1, compound example 2.
TP0463518 Chemical Structure
BCP29564 TP0463518 1558021-37-6
TP0463518 is a novel, highly potent HIF prolyl hydroxylase (PHD) inhibitor with IC50 of 13 nM and 18 nM for human and rat PHD2, respectively.
BAY 87-2243 hydrochloride Chemical Structure
BCP29477 BAY 87-2243 hydrochloride 1227158-86-2
BAY 87-2243 is a highly potent and selective inhibitor of hypoxia-induced gene activation, which has antitumor activities by inhibition of mitochondrial complex I.
VH-298 Chemical Structure
BCP20719 VH-298 2097381-85-4
VH-298 is a highly potent inhibitor of the VHL:HIF-α interaction with a Kd value of 80 to 90 nM, used in PROTAC technology.
IOX4 Chemical Structure
BCP29069 IOX4 1154097-71-8
IOX4 is a potent inhibitor of PHD2 (IC50 = 1.6 nM).
YC-1 Chemical Structure
BCP09072 YC-1 170632-47-0
YC-1(Lificiguat) is a soluble guanylyl cyclase(sGC) activator; binds to the heme-containing domain of the β subunit with Kd value of 0.6-1.1 μM in the presence of CO.
Glucosamine Chemical Structure
BCP15505 Glucosamine 3416-24-8
Glucosamine is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement.
Hydralazine hydrochloride Chemical Structure
BCP06289 Hydralazine hydrochloride 304-20-1
Hydralazine Hydrochloride is a direct-acting vasodilator that is used as an antihypertensive agent.
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