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HIF

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HIF

Chemical Structure Cat. No. Product Name CAS No.
PT-2385 R-Enantiomer Chemical Structure
BCP30945 PT-2385 R-Enantiomer 1672666-67-9
PT-2385 is a small molecule inhibitor with oral activity that inhibits hypoxia inducible factor (HIF)-2alpha heterodimerization and its subsequent binding to DNA by binding to HIF-2alpha.
Tilorone dihydrochloride Chemical Structure
BCP18046 Tilorone dihydrochloride 27591-69-1
Tilorone dihydrochloride is the first recognized synthetic, small molecular weight compound that is an orally active interferon inducer, used as an antiviral drug.
KHS101 hydrochloride Chemical Structure
BCP30178 KHS101 hydrochloride 1784282-12-7
KHS101 hydrochloride could selectively induce a neuronal differentiation phenotype and interacts with transforming acidic coiled-coil-containing protein 3 (TACC3).
KHS101 Chemical Structure
BCP30177 KHS101 1262770-73-9
KHS-101 is a small molecule that selectively induces a neuronal differentiation phenotype, induces neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs) by interacting with TACC3 (EC50=1 uM).
Desidustat Chemical Structure
BCP29692 Desidustat 1616690-16-4
Desidustat is an inhibitor of HIF hydroxylase extracted from patent WO 2014102818 A1, compound example 2.
TP0463518 Chemical Structure
BCP29564 TP0463518 1558021-37-6
TP0463518 is a novel, highly potent HIF prolyl hydroxylase (PHD) inhibitor with IC50 of 13 nM and 18 nM for human and rat PHD2, respectively.
BAY 87-2243 hydrochloride Chemical Structure
BCP29477 BAY 87-2243 hydrochloride 1227158-86-2
BAY 87-2243 is a highly potent and selective inhibitor of hypoxia-induced gene activation, which has antitumor activities by inhibition of mitochondrial complex I.
VH-298 Chemical Structure
BCP20719 VH-298 2097381-85-4
VH-298 is a highly potent inhibitor of the VHL:HIF-α interaction with a Kd value of 80 to 90 nM, used in PROTAC technology.
IOX4 Chemical Structure
BCP29069 IOX4 1154097-71-8
IOX4 is a potent inhibitor of PHD2 (IC50 = 1.6 nM).
Glucosamine Chemical Structure
BCP15505 Glucosamine 3416-24-8
Glucosamine is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement.
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