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IDO

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IDO

结构式 货号 产品名称 CAS号
NLG802 结构式
 BCP46357 NLG802 2071683-99-1
NLG802 is a prodrug of indoximod, an orally active indoleamine 2,3-dioxygenase (IDO) inhibitor.
BMS-986242 结构式
 BCP41750 BMS-986242 1923844-48-7
BMS-986242 is a novel Potent, Selective Inhibitor of Indoleamine-2,3-dioxygenase 1 (IDO1).
IACS-8968 结构式
 BCP39113 IACS-8968 2144425-14-7
IACS-8968 is a dual IDO and TDO inhibitor.
LY-3381916 结构式
 BCP33269 LY-3381916 2166616-75-5
LY-3381916(IDO1-IN-5) is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.
LM10 结构式
 BCP31973 LM10 1316695-35-8
LM10 is a selective TDO inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively)
Norharmane 结构式
 BCP20998 Norharmane 244-63-3
Norharmane is a potent IDO inhibitor
NLG919 结构式
 BCP09887 NLG919 1402836-58-1
GDC-0919, also known as NLG919 and RG6078, is an orally available inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with potential immunomodulating and antineoplastic activities.
Epacadostat 结构式
 BCP14546 Epacadostat 1204669-58-8
Epacadostat is a potent and selective IDO1 inhibitor with IC50 of 71.8 nM±17.5 nM.
IDO-IN-1 结构式
 BCP16681 IDO-IN-1 914638-30-5
IDO-IN-1 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50 of 59 nM, shows activity in Hela cell (IC50=12 nM).
IDO-IN-8 结构式
 BCP24965 IDO-IN-8 1402837-77-7
IDO-IN-8 (NLG-1487) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1487, has an IC50 of 1-10 μM.
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