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MAP4K

结构式 货号 产品名称 CAS号
GNE-495 结构式
BCP36075 GNE-495 1449277-10-4
GNE-495 is a potent and selective MAP4K4 inhibitor with an IC50 of 3.7 nM.
TAK1/MAP4K2 inhibitor 1 结构式
BCP21395 TAK1/MAP4K2 inhibitor 1 1315330-11-0
TAK1/MAP4K2 inhibitor 1 is a B-Raf inhibitor, pyrazine and pyrrolo[2,3-b]pyridine derivatives, useful in the treatment of cancer and proliferative diseases.
DMX-5084 结构式
BCP30841 DMX-5084 2306178-56-1
DMX-5804 is a potent, orally active and selective MAP4K4 inhibitor.
HG6-64-1 结构式
BCP11080 HG6-64-1 1315329-43-1
HG6-64-1 is a potent and selective B-Raf and mutant B-Raf inhibitor.HG6-64-1 is a potent dual TAK1 and MAP4K2 ((germinal center kinase, GCK)) inhibitor with IC50 of 41 nM and 98 nM, respectively.
PF-06260933 结构式
BCP28968 PF-06260933 1811510-56-1
PF-06260933 is a potent and highly selective inhibitor of MAP4K4.
PF-06260933 dihydrochloride 结构式
BCP28969 PF-06260933 dihydrochloride 1883548-86-4
PF 6260933 is a potent, selective and orally bioavailable MAP4K4 inhibitor with kinase IC50 of 3.7 nM, cell IC50 of 160 nM.
PF-06260933 HCl 结构式
BCP28970 PF-06260933 HCl 2118243-34-6
PF-06260933 dihydrochloride is a MAP4K4 (HGK) inhibitor (IC50 = 140 nM).
NCB-0846 结构式
BCP20048 NCB-0846 1792999-26-8
NCB-0846 is a novel, orally small-molecule Wnt inhibitor that inhibits TNIK (TRAF2 and NCK-Interacting Kinase) with an IC50 value of 21 nM.
NG-25 结构式
BCP28600 NG-25 1315355-93-1
NG25 is a potent dual TAK1 and MAP4K2 inhibitor.
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