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NFκB

Chemical Structure Cat. No. Product Name CAS No.
DCZ0415 Chemical Structure
 BCP33607 DCZ0415 2242470-43-3
DCZ0415 is a novel inhibitor of TRIP13, suppressing multiple myeloma progression.
KI696 Chemical Structure
 BCP33044 KI696 1799974-70-1
KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction. KI696 is a potent and selective inhibitor of the KEAP1/NRF2 interaction.
11-Keto-beta-boswellic acid Chemical Structure
 BCP32934 11-Keto-beta-boswellic acid 17019-92-0
11-Keto-beta-boswellic acid is a pentacyclic triterpenic acid of the oleogum resin from the bark of the Boswellia serrate tree, popularly known as Indian Frankincense.
GSK8612 Chemical Structure
 BCP31984 GSK8612 2361659-62-1
GSK8612 is a highly selective and potent Tank-binding Kinase-1 (TBK1) inhibitor, with a pIC50 of 6.8 for recombinant TBK1.
IKK-2 Inhibitor VIII Chemical Structure
 BCP21394 IKK-2 Inhibitor VIII 406209-26-5
IKK-2 inhibitor VIII is a potent and selective IKK-2 inhibitor with IC50 of 8.5 nM.
Methylthiouracil Chemical Structure
 BCP21374 Methylthiouracil 56-04-2
Methylthiouracil is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2.
4-Octyl Itaconate Chemical Structure
 BCP31060 4-Octyl Itaconate 3133-16-2
4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
INH14 Chemical Structure
 BCP31056 INH14 200134-22-1
INH14 is an inhibitor of the IKKα/β-dependent TLR inflammatory response.
Shikonin Chemical Structure
 BCP29329 Shikonin 517-89-5
Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin has shown various biological activities, including inhibition of TNF-α, NF-κB, HIV-1.
Eleutheroside E Chemical Structure
 BCP15731 Eleutheroside E 39432-56-9
Eleutheroside E has anti-inflammatory effect by inhibiting NF-κB activities.
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