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NFκB

Chemical Structure Cat. No. Product Name CAS No.
GSK8612 Chemical Structure
 BCP31984 GSK8612 2361659-62-1
GSK8612 is a highly selective and potent Tank-binding Kinase-1 (TBK1) inhibitor, with a pIC50 of 6.8 for recombinant TBK1.
IKK-2 Inhibitor VIII Chemical Structure
 BCP21394 IKK-2 Inhibitor VIII 406209-26-5
IKK-2 inhibitor VIII is a potent and selective IKK-2 inhibitor with IC50 of 8.5 nM.
Methylthiouracil Chemical Structure
 BCP21374 Methylthiouracil 56-04-2
Methylthiouracil is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2.
4-Octyl Itaconate Chemical Structure
 BCP31060 4-Octyl Itaconate 3133-16-2
4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
INH14 Chemical Structure
 BCP31056 INH14 200134-22-1
INH14 is an inhibitor of the IKKα/β-dependent TLR inflammatory response.
Shikonin Chemical Structure
 BCP29329 Shikonin 517-89-5
Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin has shown various biological activities, including inhibition of TNF-α, NF-κB, HIV-1.
Eleutheroside E Chemical Structure
 BCP15731 Eleutheroside E 39432-56-9
Eleutheroside E has anti-inflammatory effect by inhibiting NF-κB activities.
Ginsenoside-Rg5 Chemical Structure
 BCP10278 Ginsenoside-Rg5 186763-78-0
Ginsenoside Rg5 is a triterpenoid saponin. It has a role as a metabolite.
Rocaglamide Chemical Structure
 BCP30539 Rocaglamide 84573-16-0
Rocaglamide is a potent NF-κB activation inhibitor.
H-ALA-ALA-VAL-ALA-LEU-LEU-PRO-ALA-VAL-LEU-LEU-ALA-LEU-LEU-ALA-PRO-VAL-GLN-ARG-LYS-ARG-GLN-LYS-LEU-MET-PRO-OH Chemical Structure
 BCP30335 H-ALA-ALA-VAL-ALA-LEU-LEU-PRO-ALA-VAL-LEU-LEU-ALA-LEU-LEU-ALA-PRO-VAL-GLN-ARG-LYS-ARG-GLN-LYS-LEU-MET-PRO-OH 213546-53-3
SN50 is a cell permeable inhibitor of NF-κB translocation.
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