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NFκB

Chemical Structure Cat. No. Product Name CAS No.
DHMEQ Chemical Structure
BCP35164 DHMEQ 287194-40-5
DHMEQ is a potent NF-κB inhibitor.
Dihydrobigelovin Chemical Structure
BCP34452 Dihydrobigelovin 54999-07-4
Ergolide is a sesquiterpene lactone isolated from the dried flowers of Inula Britannica. Ergolide inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation of NF-κB.
Tyrosol Chemical Structure
BCP34277 Tyrosol 501-94-0
Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects.
DCZ0415 Chemical Structure
BCP33607 DCZ0415 2242470-43-3
DCZ0415 is a novel inhibitor of TRIP13, suppressing multiple myeloma progression.
KI696 Chemical Structure
BCP33044 KI696 1799974-70-1
KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction. KI696 is a potent and selective inhibitor of the KEAP1/NRF2 interaction.
11-Keto-beta-boswellic acid Chemical Structure
BCP32934 11-Keto-beta-boswellic acid 17019-92-0
11-Keto-beta-boswellic acid is a pentacyclic triterpenic acid of the oleogum resin from the bark of the Boswellia serrate tree, popularly known as Indian Frankincense.
GSK8612 Chemical Structure
BCP31984 GSK8612 2361659-62-1
GSK8612 is a highly selective and potent Tank-binding Kinase-1 (TBK1) inhibitor, with a pIC50 of 6.8 for recombinant TBK1.
IKK-2 Inhibitor VIII Chemical Structure
BCP21394 IKK-2 Inhibitor VIII 406209-26-5
IKK-2 inhibitor VIII is a potent and selective IKK-2 inhibitor with IC50 of 8.5 nM.
Methylthiouracil Chemical Structure
BCP21374 Methylthiouracil 56-04-2
Methylthiouracil is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2.
4-Octyl Itaconate Chemical Structure
BCP31060 4-Octyl Itaconate 3133-16-2
4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
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