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PI3K/Akt/mTOR

结构式 货号 产品名称 CAS号
RapaLink-1 结构式
BCP25153 RapaLink-1 1887095-82-0
RapaLink-1 is a third-generation mTOR inhibitor that overcomes resistance to existing first- and second-generation inhibitors.
Borussertib 结构式
BCP43065 Borussertib 1800070-77-2
Borussertib is a potent, first-in-class, covalent-allosteric AKT inhibitor.
GSK-3 Inhibitor XV 结构式
BCP42764 GSK-3 Inhibitor XV 936112-69-5
GSK3 inhibitor XV is a racemic mixture of (R)-GSK3 inhibitor XV and (S)-GSK3 inhibitor XV.
BC1618 结构式
BCP42670 BC1618 2222094-18-8
BC1618 is a novel Fbxo48 inhibitor and prevent pAmpkα degradation with MEC (minimal efficacious concentration) of 0.6 μM.
Parsaclisib hydrochloride 结构式
BCP42656 Parsaclisib hydrochloride 1995889-48-9
Parsaclisib, also known as INCB050465, is a novel PI3Kδ inhibitor which synergizes with PIM protein kinase inhibition to cause tumor regression in a model of DLBCL.
PI4KIII beta inhibitor 9 结构式
BCP41897 PI4KIII beta inhibitor 9 1429624-84-9
PI4KIIIbeta-IN-9 is a potent PI4KIIIβ inhibitor. It also inhibits PI3Kδ and PI3Kγ.
PI4KIII beta inhibitor 10 结构式
BCP41882 PI4KIII beta inhibitor 10 1881233-39-1
PI4KIIIbeta-IN-10 is a novel potent PI4KIIIβ inhibitor (IC50 3.6 nM).
PIK-108 结构式
BCP41853 PIK-108 901398-68-3
PIK-108 is an allosteric inhibitor of the lipid modifying kinases, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunits β and δ (PI3Kβ/δ).
TAS-117 结构式
BCP41128 TAS-117 1402602-94-1
TAS-117 is a PKB/Akt inhibitor potentially for the treatment of solid tumors.
PF-06679142 结构式
BCP40393 PF-06679142 1467059-66-0
PF-06679142 is a potent AMPK activator.
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