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PPAR

结构式 货号 产品名称 CAS号
Fmoc-L-Leucine 结构式
BCP39156 Fmoc-L-亮氨酸 35661-60-0
NPC 15199 is an amino acid derivative.
Lobeglitazone 结构式
BCP37672 洛贝格列酮 607723-33-1
Lobeglitazone is an agent belonging to the glitazone class of antidiabetic agents with antihyperglycemic activity. Besides its activation of peroxisome proliferator-activated receptor (PPAR) gamma, lobeglitazone is also a potent agonist for PPARalpha.
GW6471 结构式
BCP35208 GW6471 880635-03-0
GW 6471 is a potent PPARα antagonist.
LY518674 结构式
BCP34904 LY518674 425671-29-0
LY518674 is a potent, selective PPARα antagonist, with an EC50 of 42 nM for human PPARα. LY518674 reduces triglycerides in and increased HDL-C and is used for the treatment of atherosclerosis.
GW6471 结构式
BCP33242 GW6471 436159-64-7
GW6471 is a potent PPARα antagonist.
Sipoglitazar 结构式
BCP33099 Sipoglitazar 342026-92-0
Sipoglitazar is a dual peroxisome proliferator-activated receptor (PPAR) alpha and gamma agonist, with hypoglycemic activity.
Tesaglitazar 结构式
BCP23582 Tesaglitazar 251565-85-2
Tesaglitazar is a PPAR agonist potentially for the treatment of type 2 diabetes. The drug had completed several phase III clinical trials, however in May, 2006 AstraZeneca announced that it had discontinued further development.
Pioditazone hydrochloride 结构式
BCP22942 盐酸匹格列酮 112529-15-4
Pioglitazone hydrochloride is a potent and selective PPARγ agonist with EC50s of 0.93 and 0.99 μM for human and mouse PPARγ, respectively.
MK 0767 结构式
BCP30796 MK 0767 934017-32-0
MK 0767 is a dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist, has been studied as a potential treatment of type 2 diabetes and dyslipidemia.
MA-0204 结构式
BCP30365 MA-0204 2095128-17-7
MA-0204 is a potent, highly selective and orally available peroxisome proliferator activated receptor δ (PPARδ) modulator with EC50s of 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARδ, respectively. Potential treatment for Duchene Muscular Dystrophy (DMD).
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