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Protease/Metabolic Enzyme

结构式 货号 产品名称 CAS号
BAY 85-8501 结构式
BCP44126 BAY 85-8501 1161921-82-9
BAY 85-8501 is a selective, reversible and potent inhibitor of Human Neutrophil Elastase (HNE; IC50 of 65 pM)
PRL-3 Inhibitor I 结构式
BCP43976 PRL-3 Inhibitor I 893449-38-2
PRL-3 Inhibitor I is a PRL-3 inhibitor which blocks the migration and invasion of metastatic cancer cells.
Cl-Amidine 结构式
BCP43968 Cl-Amidine 1043444-18-3
Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. Cl-amidine induces apoptosis.
Razuprotafib sodium 结构式
BCP44002 Razuprotafib sodium 1809275-69-1
Razuprotafib is a protein tyrosine phosphatase ß (HPTPß) inhibitor.
L-Albizziin 结构式
BCP43980 L-脲基丙氨酸 1483-07-4
L-albizziin is a non-proteinogenic L-alpha-amino acid.
PF-06446846 结构式
BCP43978 PF-06446846 1632250-49-7
PF-06446846 is a potent, highly selective inhibitor of PCSK9 translation with IC50 of 0.3 uM for inhibition the secretion of PCSK9 by Huh7 cells.
PF-06446846 hydrochloride 结构式
BCP43977 PF-06446846 hydrochloride 1632250-50-0
PF-06446846 hydrochloride is an orally active and highly selective inhibitor of translation of Proprotein convertase subtilisin/kexin type 9 (PCSK9). PF-06446846 hydrochloride inhibits PCSK9 by inducing the ribosome to stall around codon 34.
Dapaconazole 结构式
BCP43945 Dapaconazole 1269726-67-1
Dapaconazole, as an antifungal agent, inhibits sterol 14α-demethylase cytochrome P450 activity with an IC50 of 1.4 μM.
PF-06424439 HCl 结构式
BCP43813 PF-06424439 HCl 1469284-80-7
PF 06424439 is a potent, selective and orally bioavailable Diacylglycerol Acyltransferase 2 ( DGAT2) inhibitor with DGAT2 IC50 ± SEM (nM) (human/rat/dog) 14 ± 1/38 ± 4/16 ± 1, which exhibits no significant activity at MGAT1-3 or DGAT1.
PF-06424439 Mesylate 结构式
BCP43812 PF-06424439 Mesylate 1469284-79-4
PF-06424439 Mesylate is a potent and selective inhibitor of diacylglycerol acyltransferase 2 (DGAT2).
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