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Ras/Rho

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Ras/Rho

结构式 货号 产品名称 CAS号
HJC0197 结构式
BCP43826 HJC0197 1383539-73-8
HJC0197 is a EPAC (erythromycin propionate-N-acetylcysteinate) inhibitor. EPAC inhibitor may prevent pancreatic cancer cell migration and invasion.
MCP110 结构式
BCP43521 MCP110 521310-51-0
MCP110 is an inhibitor of Ras.
MRTX1133 结构式
BCP43012 MRTX1133 2621928-55-8
MRTX1133是一种潜在的KRAS G12D特异性抑制剂,能与激活和失活状态的KRAS G12D突变体选择性地可逆结合,并且抑制其活性。
CID44216842 结构式
BCP42675 CID44216842 1222513-26-9
CID44216842 is a potent Cdc42-selective guanine nucleotide binding lead inhibitor.
BAY-293 结构式
BCP31742 BAY-293 2244904-70-7
BAY-293 is a potent SOS1 inhibitor that blocks RAS activation via disruption of the RAS-SOS1 interaction. BAY-293) selectively inhibits the KRAS-SOS1 interaction with an IC50 of 21 nM and is a valuable chemical probe for future investigations.
K-Ras-PDEδ-IN-1 结构式
BCP36418 K-Ras-PDEδ-IN-1 1841464-21-8
K-Ras-PDEδ-IN-1 is a novel and potent competitive K-Ras-PDEδ inhibitor.
KRAS inhibitor-9 结构式
BCP36417 KRAS inhibitor-9 300809-71-6
KRAS inhibitor-9, a potent KRAS inhibitor (Kd=92 μM), blocks the formation of GTP-KRAS and downstream activation of KRAS.
K-Ras G12C-IN-3 结构式
BCP36435 K-Ras G12C-IN-3 1629268-19-4
K-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C.
K-Ras G12C-IN-1 结构式
BCP36416 K-Ras G12C-IN-1 1629265-17-3
K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C.
K-Ras Degrader-1 结构式
BCP36377 K-Ras Degrader-1 2378258-52-5
PROTAC K-Ras Degrader-1 (Compound 518) is potent K-Ras degrader based PROTAC, exhibits ≥70% degradation efficacy in SW1573 cells.
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