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Reverse Transcriptase

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Reverse Transcriptase

结构式 货号 产品名称 CAS号
Emivirine 结构式
BCP43681 Emivirine 149950-60-7
Emivirine is a non-nucleoside reverse transcriptase inhibitor. Emivirine has a structure typical of a nucleoside analog but has been shown to bind directly to the reverse transcriptase and act as an NNRTI. However, it is no longer in development due to the fact that it causes an increasingly rapid breakdown of other drugs metabolized by the cytochrome P450 enzyme.
R-10015 结构式
BCP37585 R-10015 2097938-51-5
R-10015, a broad-spectrum antiviral compound for HIV infection, acts as a potent and selective inhibitor of LIM domain kinase (LIMK) and binds to the ATP-binding pocket, with an IC50 of 38 nM for human LIMK1.
Nevirapine 结构式
BCP05587 奈韦拉平 129618-40-2
Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM.
Ro 0335 结构式
BCP28161 Ro 0335 867365-76-2
Ro-0335 is a novel diphenylether nonnucleoside reverse transcriptase inhibitor.
AVX754 结构式
BCP07907 阿立他滨 160707-69-7
Apricitabine, also known as (-)-BCH-10652; (-)-dOTC; AVX-754; BCH-10618; SPD-754, is an experimental nucleoside reverse transcriptase inhibitor (NRTI) against HIV.
Foscarnet sodium 结构式
BCP14044 膦甲酸钠 63585-09-1
Foscarnet Sodium inhibits viral RNA polymerases, reverse transcriptase, and DNA polymerases through noncompetitive inhibition with dNTPs.
Zidovudine 结构式
BCP03622 齐多夫定 30516-87-1
Zidovudine (Retrovir) is a reverse transcriptase inhibitor.
Fangchinoline 结构式
BCP26186 防己诺林碱 436-77-1
Fangchinoline is an isolate from Stephania Tetrandra that shows anti-cancer activity. It inhibits breast adenocarcinoma proliferation through apoptosis induction. In addition, it has been shown to inhibit HIV-Type 1 replication.
Entecavir 结构式
BCP02292 恩替卡韦 142217-69-4
Entecavir is a deoxyguanosine nucleoside analogue with antiviral activity against the hepatitis B virus (HBV).
Entecavir hydrate 结构式
BCP01930 恩替卡韦一水合物 209216-23-9
Entecavir is a nucleoside analog that inhibits reverse transcription.
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