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SGLT

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SGLT

结构式 货号 产品名称 CAS号
Licogliflozin 结构式
BCP35901 Licogliflozin 1291094-73-9
Licogliflozin is a sodium glucose cotransporter (SGLT1 and SGLT2) inhibitor.
Mizagliflozin 结构式
BCP35148 Mizagliflozin 666843-10-3
Mizagliflozin (DSP-3235, KGA-3235, GSK-1614235) is a potent, orally active and selective SGLT1 inhibitor, with a Ki of 27 nM for human SGLT1. Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic drug that can modify postprandial blood glucose excursion. Mizagliflozin also exhibits potential in the amelioration of chronic constipation.
LX2761 结构式
BCP26031 LX2761 1610954-97-6
LX2761 is chemically stable and potent inhibitor against sodium-dependent glucose cotransporter 1 (SGLT1) and SGLT2 in vitro with IC50s of 2.2 nM and 2.7nM for hSGLT1 and hSGLT2, but displays specific SGLT1 inhibition in the gastrointestinal (GI) tract.
Sergliflozin Etabonate 结构式
BCP09291 依碳酸舍格列净 408504-26-7
Sergliflozin etabonate is a SGLT-2 inhibitor potentially for the treatment of type 2 diabetes and obesity.
Canagliflozin Hydrate 结构式
BCP19353 坎格列净一水物 1809403-05-1
Canagliflozin hydrate is a glucoside-derived SODIUM-GLUCOSE TRANSPORTER 2 inhibitor that stimulates urinary excretion of glucose by suppressing renal glucose reabsorption.
Remogliflozin etabonate 结构式
BCP16294 瑞格列净乙酸酯 442201-24-3
Remogliflozin Etabonate is an orally available prodrug of remogliflozin, a benzylpyrazole glucoside-based inhibitor of renal sodium-glucose co-transporter subtype 2 (SGLT2) with antihyperglycemic activity.
Phlorizin 结构式
BCP29914 Phlorizin 60-81-1
Phlorizin is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor.
Luseogliflozin 结构式
BCP20937 鲁格列净 898537-18-3
Luseogliflozin, also known as TS-71 and TS-071, is a potent and competitive inhibitor of sodium-dependent glucose cotransporter 2 (SGLT2 inhibitor).
Ipragliflozin L-proline 结构式
BCP28794 L-脯氨酸伊格列净 951382-34-6
Ipragliflozin is a Sodium/glucose cotransporter 2 (SGLT2) inhibitor (gliflozin).
Ipragliflozin 结构式
BCP07718 伊格列净 761423-87-4
Ipragliflozin (ASP1941) is a highly potent and selective SGLT2 inhibitor with IC50 of 2.8 nM; little and NO potency for SGLT1/3/4/5/6.
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