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Sirtuin

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Sirtuin

结构式 货号 产品名称 CAS号
SIRT-IN-2 结构式
BCP41849 SIRT-IN-2 1431411-66-3
SIRT-IN-2 is a potent inhibitor of SIRT1/2/3, with IC50s of 4, 4, 7 μM, respectively.
Selisistat S-enantiomer 结构式
BCP41219 Selisistat S-enantiomer 848193-68-0
EX-527 S-enantiomer is the S-enantiomer of EX-527, which is a potent and selective SIRT1 inhibitor and with no inhibition on SIRT3 and SIRT3.
SBI-797812 结构式
BCP39800 SBI-797812 2237268-08-3
SBI-797812 is a novel NAMPT activator, elevating liver NAD+, turning NAMPT into a "super catalyst" that more efficiently generates NMN.
4'-Bromo-resveratrol 结构式
BCP37824 4'-Bromo-resveratrol 1224713-90-9
4'-Bromo-resveratrol is a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3).
UBCS039 结构式
BCP37615 UBCS039 358721-70-7
UBCS039 is the first synthetic Sirt6 activator.
SRT2183 结构式
BCP37408 SRT2183 1001908-89-9
SRT 2183 is a selective Sirtuin-1 (SIRT1) activator with an EC1.5 value of 0.36 μM. SRT 2183 induces growth arrest and apoptosis, concomitant with deacetylation of STAT3 and NF-κB, and reduction of c-Myc protein levels.
CAY10602 结构式
BCP32626 CAY10602 374922-43-7
CAY10602 is a SIRT1 activator.
DMNQ 结构式
BCP31298 DMNQ 6956-96-3
DMNQ is a superoxide generating agent. DMNQ mimicks high glucose-suppressed SIRT2 and SIRT6 expression.
Acetyl-trans-resveratrol 结构式
BCP24098 乙酰基白藜芦醇 42206-94-0
Triacetyl resveratrol is Resveratrol prodrug.
Cambinol 结构式
BCP28973 Cambinol 14513-15-6
Cambinol is a SIRT1 and SIRT2 inhibitor with IC50 values of 56 and 59 μM, respectively.
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