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TNF Receptor

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TNF Receptor

结构式 货号 产品名称 CAS号
UCB-9260 结构式
BCP40717 UCB-9260 1515888-53-5
UCB-9260 is an orally active inhibitor that inhibits TNF signalling by stabilising an asymmetric form of the trimer.
(Rac)-Benpyrine 结构式
BCP37768 (Rac)-Benpyrine 1333714-43-4
(Rac)-Benpyrine is a racemate of Benpyrine. (Rac)-Benpyrine is a potent and orally active TNF-α inhibitor and has the potential for TNF-α mediated inflammatory and autoimmune disease research.
Corilagin 结构式
BCP25487 柯里拉京 23094-69-1
Corilagin, discovered in many medicinal plants such as Phyllanthus speices etc., has multiple activities including anti-oxidative, anti-inflammatory, anti-apoptotic, hepatoprotective and others. It is an inhibitor of TNF-α.
Hispidol 结构式
BCP32790 Hispidol 5786-54-9
Hispidol is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon epithelial cells with an IC50 of 0.50 µM.
Methylthiouracil 结构式
BCP21374 甲基硫脲嘧啶 56-04-2
Methylthiouracil is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2.
Shikonin 结构式
BCP29329 紫草素 517-89-5
Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin has shown various biological activities, including inhibition of TNF-α, NF-κB, HIV-1.
C25-140 结构式
BCP30323 C25-140 1358099-18-9
C25-140 is the first in class protein-protein interaction inhibitor of a RING-E3 ligase (TRAF6) / E2 enzyme (Ubc13) binding.
Golimumab 结构式
BCP30499 戈利木单抗 476181-74-5
Golimumab (CNTO 148) is a human monoclonal antibody which is used as an immunosuppressive drug. Golimumab targets tumor necrosis factor alpha (TNF-alpha), a pro-inflammatory molecule and hence is a TNF inhibitor.
Etanercept 结构式
BCP12862 依那西普 185243-69-0
Etanercept is a dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.
AX-024 结构式
BCP30051 AX-024 1370544-73-2
AX-024 is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
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