Lidocaine hydrochloride
CAS No. | 73-78-9 | Cat. No. | BCP30473 |
Name | Lidocaine hydrochloride | ||
Synonyms | Lignocaine hydrochloride;Lidocaine HCl; | ||
Formula | C14H23ClN2O | M. Wt | 270.80 |
Description | Lidocaine Hydrochloride is the hydrochloride salt from of lidocaine, an aminoethylamide and a prototypical member of the amide class anesthetics. Lidocaine interacts with voltage-gated Na+ channels in the nerve cell membrane and blocks the transient increase in permeability of excitable membranes to Na+. This prevents the generation and conduction of nerve impulses and produces a reversible loss of sensation. Lidocaine hydrochloride also exhibits class IB antiarrhythmic effects. The agent decreases the flow of sodium ions into myocardial tissue, especially on the Purkinje network, during phase 0 of the action potential, thereby decreasing depolarization, automaticity and excitability. |
Structure
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