磷酸氯喹
| CAS号 | 50-63-5 | 货号 | BCP31956 |
| 中文名 | 磷酸氯喹 | ||
| 英文名 | Chloroquine diphosphate | ||
| 中文别名 | 磷酸氯化喹啉;二磷酸氯喹;7-氯-4-(4-二乙氨基-1-甲基丁氨基)喹啉二磷酸盐; | ||
| 英文别名 | Chloroquine phosphate;Aralen phosphate;7-chloro-4-((4’-diethylamino-1-methylbutyl)amino)quinolinediphosphate; | ||
| 分子式 | C18H32ClN3O8P2 | 分子量 | 515.86 |
| 生物活性 | Chloroquine Phosphate is the phosphate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. Chloroquine may also interfere with the biosynthesis of nucleic acids. | ||
| 信号通路 | Microbiology/Virology Others Pathway | ||
| 靶 点 | SARS CoV TLR HIV | ||
结构式
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