IWP-O1
| CAS号 | 2074607-48-8 | 货号 | BCP41115 |
| 中文名 | IWP-O1 | ||
| 英文名 | IWP-O1 | ||
| 中文别名 | |||
| 英文别名 | IWPO1; IWP O1; | ||
| 分子式 | C26H20N6O | 分子量 | 432.48 |
| 生物活性 | IWP-O1 is highly potent Porcn inhibitor, The acyltransferase Porcupine (Porcn) is essential for the secretion of Wnt proteins which contribute to embryonic development, tissue regeneration, and tumorigenesis. IWP-O1 has an EC50 value of 80pM in a cultured cell reporter assay of Wnt signaling. Additionally, IWP-O1 has significantly improved metabolic stability over our previously reported Porcn inhibitors. | ||
| 信号通路 | Wnt/Stem Cell | ||
| 靶 点 | Wnt | ||
结构式
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