Succinyl phosphonate trisodium salt

  • Chemical Properties
CAS No. 864167-45-3 Cat. No. BCP42841
Name Succinyl phosphonate trisodium salt
Synonyms
Formula C4H4Na3O6P M. Wt 248.01
  • Biological Activity
Description Succinyl phosphonate trisodium salt is an α-ketoglutarate dehydrogenase (KGDHC) inhibitor, effective inhibits (KGDHC) in muscle, bacterial, brain, and cultured human fibroblasts. Succinyl phosphonate trisodium salt is an 2-oxoglutarate dehydrogenase (OGDH) inhibitor, impairs viability of cancer cells in a cell-specific metabolism-dependent manner. Succinyl phosphonate trisodium salt inhibits the glutamate-induced ROS production in glutamate-stimulated hippocampal neurons in situ.

Structure

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