Box5
| CAS号 | 881188-48-3 | 货号 | BCP46893 |
| 中文名 | Box5 | ||
| 英文名 | Box5 | ||
| 中文别名 | |||
| 英文别名 | Box-5;Box 5; | ||
| 分子式 | C25H42N6O11S2 | 分子量 | 666.76 |
| 生物活性 | Box5 is a Wnt5a-derived N-butyloxycarbonyl hexapeptide (t-Boc-Met-Asp-Gly-Cys-Glu-Leu), acts as an Wnt5a antagonist; abolishes exogenous Wnt5a stimulation of A2058 cells increased adhesion, migration and invasion, all crucial components of tumor metastasis, also inhibits the basal migration and invasion of Wnt5a-expressing HTB63 melanoma cells, antagonizes the effects of Wnt5a on melanoma cell migration and invasion by directly inhibiting Wnt5a-induced PKC and Ca(2+) signaling. | ||
| 信号通路 | Wnt/Stem Cell | ||
| 靶 点 | Wnt | ||
结构式
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