VGL-101

Chemical Properties

CAS No.	2733621-19-5	Cat. No.	BCP49368
Name	VGL-101
Synonyms	Iluzanebart;VGL101;VGL 101;
Formula		M. Wt

Biological Activity

Description	VGL101 is a humanized monoclonal antibody that acts as an agonist for TREM2. This receptor is expressed on microglia and macrophages, and mediates their proliferation and function. VGL101 is claimed to activate TREM2 signaling with sub-nanomolar potency and selectivity.

Description

VGL101 is a humanized monoclonal antibody that acts as an agonist for TREM2. This receptor is expressed on microglia and macrophages, and mediates their proliferation and function. VGL101 is claimed to activate TREM2 signaling with sub-nanomolar potency and selectivity.

Structure

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