GSK 650394
  • Chemical Properties
CAS No. 890842-28-1 Cat. No. BCP08392
Name GSK 650394
Synonyms GSK-650394; GSK650394;
Formula C25H22N2O2 M. Wt 382.45
  • Biological Activity
Description Serum- and glucocorticoid-regulated kinase 1 (SGK1) inhibitor (IC50 values are 62 and 103 nM for SGK1 and SGK2 respectively). Displays >30-fold selectivity over Akt and other related kinases. Inhibits androgen-stimulated growth of LNCaP cells, a human prostate carcinoma cell line (IC50 ~ 1 μM).
  • Publications Citing
Inhibition of SGK1 confers vulnerability to redox dysregulation in cervical cancer

Publications Citing of Biochempartner's GSK 650394(CAS:890842-28-1)

Structure

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