Moxonidine

Description	Moxonidine is a centrally acting antihypertensive drug that is selective agonist at the imidazoline receptor subtype 1 (I1). This receptor subtype is found in both the rostral ventro-lateral pressor and ventromedial depressor areas of the medulla oblongata. Moxonidine therefore causes a decrease in sympathetic nervous system activity and a decrease in blood pressure. Moxonidine may also promote sodium excretion, improve insulin resistance and glucose tolerance and protect against hypertensive target organ damage, such as kidney disease and cardiac hypertrophy.
Pathways	Neuro Signaling Pathway
Targets	Imidazoline Receptor

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