Roxadustat
| CAS No. | 808118-40-3 | Cat. No. | BCP02523 |
| Name | Roxadustat | ||
| Synonyms | ASP1517; ASP 1517; ASP-1517; FG4592;FG 4592;FG-4592; | ||
| Formula | C19H16N2O5 | M. Wt | 352.34 |
| Description | Roxadustat, also known as ASP1517 and FG-4592, is an HIF α prolyl hydroxylase inhibitor in a cell-free assay. It stabilizes HIF-2 and induces EPO production and stimulates erythropoiesis. Roxadustat transiently and moderately increased endogenous erythropoietin and reduced hepcidin. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | HIF | ||
Structure
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