IRL-1620
| CAS号 | 142569-99-1 | 货号 | BCP09112 |
| 中文名 | IRL-1620 | ||
| 英文名 | IRL-1620 | ||
| 中文别名 | |||
| 英文别名 | SPI-1620; IRL1620; IRL 1620; | ||
| 分子式 | C86H117N17O27 | 分子量 | 1820.95 |
| 生物活性 | IRL-1620, also known as SPI-1620, is an endothelin B receptor agonist. SPI-1620 is a highly selective peptide agonist of the endothelin-B receptor. Endothelin B receptor agonist SPI-1620 binds to endothelin-B receptors on endothelial cells in tumor blood vessels, which, unlike the angioarchitecture of normal blood vessels, are relatively devoid of smooth muscle. This agent may induce a transient, selective increase in blood flow to a tumor, which may result in an increase in the delivery of anticancer agents to the tumor and, so, an increase in anticancer agent efficacy. | ||
| 信号通路 | GPCR/G Protein | ||
| 靶 点 | Endothelin Receptor | ||
结构式
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