盐酸吗啉吲酮

  • 化学数据
CAS号 15622-65-8 货号 BCP09555
中文名 盐酸吗啉吲酮
英文名 Monohydrochloride
中文别名 盐酸吗茚酮;
英文别名 Molindone HCl; Molindone hydrochloride;EN 1733A;Lindone;
分子式 C16H25ClN2O2 分子量 312.83
  • 用途
生物活性 Molindone Hydrochloride is the hydrochloride salt form of molindone, a dihydroindolone compound with antipsychotic and anti-schizophrenic properties not structurally related to other major tranquilizers. Molindone hydrochloride exerts its effect by blocking dopamine receptors, probably D2 and D3, in the reticular activating and limbic systems, thereby decreasing dopamine excess in the brain. This leads to a reduction of spontaneous locomotion and aggressiveness, suppression of conditioned response, antagonism of stereotyped behaviour and hyperactivity induced by amphetamines.
信号通路 Neuro Signaling Pathway GPCR/G Protein 
靶 点 Dopamine Receptor 

结构式

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