LCZ696

  • Chemical Properties
CAS No. 936623-90-4 Cat. No. BCP10630
Name LCZ696
Synonyms LCZ-696; LCZ 696;Entresto;Valsartan/sacubitril;Sacubitril mixture with Valsartan;
Formula C48H55N6O8Na3 M. Wt 912.97
  • Biological Activity
Description LCZ696 is a first in class ARNi (angiotensin receptor neprilysin inhibitor) comprising anionic moieties of AR valsartan and the neprilysin inhibitor prodrug AHU377 (1:1 ratio) for heart failure and hypertension.
Pathways Protease/Metabolic Enzyme GPCR/G Protein 
Targets Angiotensin Receptor Neprilysin 

Structure

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