CB-839
| CAS号 | 1439399-58-2 | 货号 | BCP28287 |
| 中文名 | CB-839 | ||
| 英文名 | CB-839 | ||
| 中文别名 | |||
| 英文别名 | CB839; CB 839；Telaglenastat,; | ||
| 分子式 | C26H24F3N7O3S | 分子量 | 571.57 |
| 生物活性 | CB-839 is an orally bioavailable inhibitor of glutaminase, with potential antineoplastic activity. CB-839 selectively and irreversibly inhibits glutaminase. By blocking glutamine utilization, proliferation in rapidly growing cells is impaired. Glutamine-dependent tumors rely on the conversion of exogenous glutamine into glutamate and glutamate metabolites to both provide energy and generate building blocks for the production of macromolecules, which are needed for cellular growth and survival. | ||
| 信号通路 | Others Pathway | ||
| 靶 点 | Autophagy | ||
|
Metabolic intervention liposome for targeting glutamine-addiction of breast cancer
购于瀚香生物(Biochempartner)的CB-839(CAS:1439399-58-2)被引用 |
结构式
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