炔诺酮醋酸酯
| CAS号 | 51-98-9 | 货号 | BCP11908 |
| 中文名 | 炔诺酮醋酸酯 | ||
| 英文名 | Norethindrone Acetate | ||
| 中文别名 | 醋酸炔诺酮; | ||
| 英文别名 | Norethisterone acetate; 19-Norethindrone acetate; | ||
| 分子式 | C22H28O3 | 分子量 | 340.46 |
| 生物活性 | Norethindrone Acetate is the orally bioavailable acetate salt of norethindrone, a synthetic progestin with some anabolic, estrogenic, and androgenic activities. As do all progestins, norethindrone binds to and activates nuclear progesterone receptors (PRs) in target tissues such as the pituitary and reproductive system; ligand-receptor complexes are translocated to the nucleus where they bind to progesterone response elements (PREs) located on target genes, followed by various transcriptional events and histone acetylation. Physiological effects include the inhibition of luteinizing hormone (LH) release, an increase in the endometrial luteal-phase, and alterations in endocervical mucus secretion. | ||
| 信号通路 | Hormone Pathay | ||
| 靶 点 | Progesterone Receptor | ||
结构式
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