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m-PEG4-bromide Chemical Structure

m-PEG4-bromide

Data Sheet For research use only. Not for human use.
Cat. No. :BCP42805CAS No. :110429-45-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 110429-45-3 Cat. No. BCP42805
Name m-PEG4-bromide
Synonyms 13-Bromo-2,5,8,11-tetraoxatridecane;Triethylene Glycol 2-Bromoethyl Methyl Ether;
SMILES COCCOCCOCCOCCBr
Chemical Name
Formula C9H19BrO4 M. Wt 271.15
Purity 98% Storage Store at 4-8°C
Description m-PEG4-Br is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) for Trastuzumab. m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency. m-PEG4-Br also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.
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