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SGI-7079 Chemical Structure

SGI-7079

Data Sheet For research use only. Not for human use.
Cat. No. :BCP21014CAS No. :1239875-86-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1239875-86-5 Cat. No. BCP21014
Name SGI-7079
Synonyms SGI 7079; SGI707;
SMILES N#CCC1=CC=CC(C2=C3C(NC=C3C)=NC(NC4=CC=C(N5CCN(C)CC5)C(F)=C4)=N2)=C1
Chemical Name
Formula C26H26FN7 M. Wt 455.54
Purity 98% Storage Store at 4-8°C
Description SGI-7079 is a potent and selective Axl inhibitor with potential anticancer activity. SGI-7079 effectively inhibited Axl activation in the presence of exogenous Gas6 ligand. SGI-7079 inhibited tumor growth in a dose dependent manner. Axl is a potential therapeutic target for overcoming EGFR inhibitor resistance.
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