GNE-9822 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1557232-32-2 | Cat. No. | BCP48535 |
| Name | GNE-9822 | ||
| Synonyms | GNE 9822; GNE9822; | ||
| SMILES | CC1(CCC2=C(C1)NN=C2C(=O)NC3=CN(N=C3)C(CCN(C)C)C4=CC=CC=C4)C | ||
| Chemical Name | |||
| Formula | C24H32N6O | M. Wt | 420.55 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | GNE-9822 is a potent and selective ITK inhibitor. GNE-9822 shows good ADME properties in preclinical species. Interleukin-2 inducible T-cell kinase (ITK), a member of the Tec family of tyrosine kinases, plays a major role in T-cell signaling downstream of the T-cell receptor (TCR), and considerable efforts have been directed toward discovery of ITK-selective inhibitors as potential treatments of inflammatory disorders such as asthma. | ||
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