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MC-VAL-CIT-PAB-CL Chemical Structure

MC-VAL-CIT-PAB-CL

Data Sheet For research use only. Not for human use.
Cat. No. :BCP42803CAS No. :1639351-92-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1639351-92-0 Cat. No. BCP42803
Name MC-VAL-CIT-PAB-CL
Synonyms
SMILES O=C(N1CCCCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(CCl)C=C2)=O)=O)=O)C=CC1=O
Chemical Name
Formula C28H39ClN6O6 M. Wt 591.1
Purity 98% Storage Store at 4-8°C
Description Mc-Val-Cit-PAB-Cl is an ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay).
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