MC-VAL-CIT-PAB-CL New
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CAS No. | 1639351-92-0 | Cat. No. | BCP42803 |
Name | MC-VAL-CIT-PAB-CL | ||
Synonyms | |||
SMILES | O=C(N1CCCCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(CCl)C=C2)=O)=O)=O)C=CC1=O | ||
Chemical Name | |||
Formula | C28H39ClN6O6 | M. Wt | 591.1 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Mc-Val-Cit-PAB-Cl is an ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay). |
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