Eritoran New

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP25714CAS No. ：185955-34-4Purity：98%

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CAS No.	185955-34-4	Cat. No.	BCP25714
Name	Eritoran
Synonyms	B-1287; B1287; B 1287; E 5564; E-5564; E5564;
SMILES	CCCCCCCCCCCC(=O)CC(=O)NC1C(C(C(OC1OP(=O)(O)O)COC2C(C(C(C(O2)COC)OP(=O)(O)O)OCCC(CCCCCCC)OC)NC(=O)CCCCCCCCCC=CCCCCCC)O)OCCCCCCCCCC
Chemical Name
Formula	C66H126N2O19P2	M. Wt	1313.66
Purity	98%	Storage	Store at 4-8°C
Description	Eritoran is a synthetic analogue of the lipid A portion of the endotoxin lipopolysaccharide (LPS) with potential immunomodulating activity. Eritoran binds to a receptor complex composed of toll-like receptor 4 (TLR4), CD14 and MD2 (MD-2, LY96) that is present on most cells of the immune system, inhibiting the activation of the receptor complex by LPS, which may result in the inhibition of pro-inflammatory cytokine secretion and a potentially fatal systemic inflammatory response syndrome (SIRS). LPS is found in the outer membrane of Gram-negative bacteria and binds to the TLR4/CD14/MD2 receptor complex of immune cells, including macrophages, resulting in the release of pro-inflammatory cytokines.