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KYA1797K Chemical Structure

KYA1797K

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP29963CAS No. ：1956356-56-1Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1956356-56-1 Cat. No. BCP29963
Name KYA1797K
Synonyms KYA1797K potassium salt;
SMILES C1=CC(=CC=C1C2=CC=C(O2)C=C3C(=O)N(C(=S)S3)CCC(=O)[O-])[N+](=O)[O-].[K+]
Chemical Name
Formula C17H11N2O6S2.K M. Wt 442.50
Purity 98% Storage Store at 4-8°C
Description KYA1797K is an inhibitor of both Wnt/β-catenin and Ras pathways. It binds to the axin regulators of the G-protein signaling (RGS) domain enhancing formation of the β-catenin destruction complex and inducing activation GSK3β, which results in phosphorylation and subsequent degradation of both β-catenin and K-Ras. KYA1797K was show to suppress tumor growth and progression in mouse xenografts of CRC cells that had APC and K-Ras mutations.
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