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EGFR-IN-7 Chemical Structure

EGFR-IN-7

Data Sheet For research use only. Not for human use.
Cat. No. :BCP34208CAS No. :2267329-76-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2267329-76-8 Cat. No. BCP34208
Name EGFR-IN-7
Synonyms TQB3804;
SMILES CN1CCN(C2CCN(C3=C(C)C=C(NC4=NC=C(Br)C(NC5=CC=C6N=CC=NC6=C5P(C)(C)=O)=N4)C(OC)=C3)CC2)CC1
Chemical Name
Formula C32H41BrN9O2P M. Wt 694.60
Purity 98% Storage Store at 4-8°C
Description EGFR-IN-7 is a selective and potent EGFR kinase inhibitor extracted from patent WO2019015655A1, has IC50s of 7.92 nM and 0.218 nM for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) respectively, and shows anti-tumor activity.
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