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CAS No. | 2377858-38-1 | Cat. No. | BCP42678 |
Name | SCR130 | ||
Synonyms | SCR-130;SCR 130; | ||
SMILES | O=C1NC(NC(C12N=C(CC2C3=CC=C(C=C3)Cl)C4=CC=C(Cl)C=C4)=O)=S | ||
Chemical Name | |||
Formula | C19H13Cl2N3O2S | M. Wt | 418.30 |
Purity | 98% | Storage | Store at 4-8°C |
Description | SCR130 is a SCR7-based DNA nonhomologous end-joining (NHEJ) inhibitor. SCR130 inhibits the end-joining of DNA in a Ligase IV-dependent manner. SCR130 is specific to Ligase IV, and shows minimal or no effect on Ligase III and Ligase I mediated joining. SCR130 induces cell apoptosis and has anticancer activity. |
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