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CAS No. | 2640567-43-5 | Cat. No. | BCP45858 |
Name | INE963 | ||
Synonyms | NVP-INE963; INE 963; INE-963; | ||
SMILES | CC(C)C1=NC(=C(C=C1)C2=CN=C3N2N=C(S3)N4CCC(CC4)(CN)O)OC | ||
Chemical Name | |||
Formula | C19H26N6O2S | M. Wt | 402.51 |
Purity | 98% | Storage | Store at 4-8°C |
Description | INE963 is a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncomplicated Malaria. INE963 demonstrates potent cellular activity against Pf 3D7 (EC50 = 0.006 μM) and achieves “artemisinin-like” kill kinetics in vitro with a parasite clearance time of <24 h. |
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