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Dapagliflozin Chemical Structure

Dapagliflozin

Data Sheet For research use only. Not for human use.
Cat. No. :BCP01880CAS No. :461432-26-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 461432-26-8 Cat. No. BCP01880
Name Dapagliflozin
Synonyms BMS-512148;BMS512148;BMS 512148;
SMILES O[C@]1[C@](C2=CC(CC3=CC=C(OCC)C=C3)=C(Cl)C=C2)O[C@](CO)[C@@H](O)[C@@H]1O
Chemical Name
Formula C21H25ClO6 M. Wt 408.87
Purity 98% Storage Store at 4-8°C
Description Dapagliflozin, also known as BMS-512148, is a drug used to treat type 2 diabetes approved in 2012 by FDA. Dapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2) which are responsible for at least 90% of the glucose reabsorption in the kidney. Blocking this transporter mechanism causes blood glucose to be eliminated through the urine. In clinical trials, dapagliflozin lowered HbA1c by 0.6 versus placebo percentage points when added to metformin.
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