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Gigantol Chemical Structure

Gigantol

Data Sheet For research use only. Not for human use.
Cat. No. :BCP29252CAS No. :67884-30-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 67884-30-4 Cat. No. BCP29252
Name Gigantol
Synonyms Dendrophenol;
SMILES
Chemical Name
Formula C16H18O4 M. Wt 274.31
Purity 98% Storage Store at 4-8°C
Description Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. It inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells. Gigantol may be developed as a promising neuroprotective agent for successful MSC transplantation in ischemic diseases, it shows protective effect against hydrogen peroxide-induced apoptosis in rat bone marrow mesenchymal stem cells through the PI3K/Akt pathway.Gigantol inhibits aldose reductase gene to exert its anti-cataract activity. Gigantol induces growth inhibition and apoptosis of HepG2 cells via the PI3K/Akt/NF-κB signaling pathway.Gigantol shows α-glucosidase inhibitory activity.
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