JK-P3 New
Data Sheet
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| CAS No. | 942655-44-9 | Cat. No. | BCP32785 |
| Name | JK-P3 | ||
| Synonyms | 3,4-Dimethoxy-N-(5-phenyl-1H-pyrazol-3-yl)-benzamide; | ||
| SMILES | COC1=C(C=C(C=C1)C(=O)NC2=NNC(=C2)C3=CC=CC=C3)OC | ||
| Chemical Name | |||
| Formula | C18H17N3O3 | M. Wt | 323.34 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | JK-P3 is novel inhibitor of VEGFR-2. JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50 = 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation. | ||
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